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EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled

Catalog No. TMPK-00425
Synonyms: EC 2.7.10.1, HER1, EGFR, PIG61, LEGFR, ErbB, ERBB1, mENA, EC 2.7.10, NISBD2

The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.

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EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 1,400.00
500 μg 5 days $ 3,720.00
1 mg 5 days $ 6,210.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.
Species Human
Expression System HEK293
Tag C-His-Avi
Accession Number P00533-1
Synonyms EC 2.7.10.1, HER1, EGFR, PIG61, LEGFR, ErbB, ERBB1, mENA, EC 2.7.10, NISBD2
Construction Recombinant FITC-Labeled Human EGFR/HER1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Leu25-Ser645.[Accession |P00533-1]
Protein Purity > 95% as determined by Tris-Bis PAGE
Molecular Weight The protein has a predicted MW of 71.5 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per ug by the LAL method.
Formulation Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Stability & Storage

Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.

References and Literature

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Keywords

EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled EC 2.7.10.1 HER1 EGFR PIG61 NISBD-2 HER 1 LEGFR ERBB 1 PIG 61 ErbB ERBB1 ERBB-1 mENA HER-1 EC 2.7.10 PIG-61 NISBD2 NISBD 2 recombinant recombinant-proteins proteins protein

 

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