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Anti-TBG Antibody (9P797) is a Mouse antibody targeting TBG. Anti-TBG Antibody (9P797) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-TBG Antibody (9P797) is a Mouse antibody targeting TBG. Anti-TBG Antibody (9P797) can be used in ELISA. |
Alias | Thyroxine Binding Globulin, TBG, serpin peptidase inhibitor, clade A (α-1 antiproteinase, antitrypsin), member 7, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7, Serpin A7 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 9P797 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SerpinA7 (rh SerpinA7; TMPY-01256; NP_000345.2; Met1-Ala415). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein that belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG binds thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 and T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human SerpinA7 protein (TMPY-01256) |
Antigen Species | Human |
Biology Area | Serine Proteases and Regulators |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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