Siglec-10 Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00363 Copy Product Info

Siglec-10 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 62.64 kDa and the accession number is Q96LC7-1.

Siglec-10 Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00363

Copy Product Info

Siglec-10 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 62.64 kDa and the accession number is Q96LC7-1.

Pack Size	Price	USA Stock	Global Stock
5 μg	$58	7-10 days	7-10 days
10 μg	$92	7-10 days	7-10 days
20 μg	$148	7-10 days	7-10 days
50 μg	$289	7-10 days	7-10 days
100 μg	$487	7-10 days	7-10 days
200 μg	$883	7-10 days	7-10 days
500 μg	$1,950	7-10 days	7-10 days

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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Information

Biological Activity	Immobilized Human Siglec-10 (R119A) , His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-Siglec-10 (R119A) Antibody, hFc Tag with the EC50 of 19.8ng/ml determined by ELISA.
Description	Siglec-10 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 62.64 kDa and the accession number is Q96LC7-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	Q96LC7-1
Synonyms	SLG2,SIGLEC10,PRO940,MGC126774
Construction	Met17-Thr546
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	62.64 kDa (predicted). Due to glycosylation, the protein migrates to 65-80 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 150 mM NaCl, 200 mM Arginine (pH 8.0). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.