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HER3/ERBB3 Protein, Human, Recombinant

(Synonyms: p85-sErbB3, p45-sErbB3, p180-ErbB3, MDA-BF-1, LCCS2, HER3, erbB3-S, ErbB-3, erb-b2 receptor tyrosine kinase 3, EEBB3, c-erbB-3, c-erbB3) Copy Product Info

Synonyms: p85-sErbB3, p45-sErbB3, p180-ErbB3, MDA-BF-1, LCCS2, HER3, erbB3-S, ErbB-3, erb-b2 receptor tyrosine kinase 3, EEBB3, c-erbB-3, c-erbB3

Catalog No. TMPY-00399 Copy Product Info
HER3/ERBB3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.3 kDa and the accession number is P21860-1.

Batch Information

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Purity:92.6%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Immobilized Recombinant Human HER3/ErbB3 Protein (Cat#TMPY-00399) at 2 μg/mL (100 μL/well) can bind Anti-Human Her3 Antibody, Human IgG1, the EC50 is 3-12 ng/mL (QC tested).
Description
HER3/ERBB3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.3 kDa and the accession number is P21860-1.
Species
Human
Expression System
HEK293 Cells
TagTag Free
Accession NumberP21860-1
ConstructionA DNA sequence encoding the human ERBB3 (NP_001973.2) (Met1-Thr643) was expressed with five amino acids (DDDDK) at the C-terminus. Predicted N terminal: Ser 20
Protein Purity
> 85 % as determined by SDS-PAGE
HER3/ERBB3 Protein, Human, Recombinant
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionReconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonymsp85-sErbB3, p45-sErbB3, p180-ErbB3, MDA-BF-1, LCCS2, HER3, erbB3-S, ErbB-3, erb-b2 receptor tyrosine kinase 3, EEBB3, c-erbB-3, c-erbB3
Research Background
Chemical Properties
Molecular Weight69.3 kDa (predicted)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: HER3/ERBB3 Protein, Human, Recombinant chemical structure | HER3/ERBB3 Protein, Human, Recombinant molecular weight