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tetranor-PGAM

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Catalog No. T38305Cas No. 52510-53-9

Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine.

tetranor-PGAM

tetranor-PGAM

😃Good
Catalog No. T38305Cas No. 52510-53-9
Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μg$43035 days35 days
50 μg$83835 days35 days
100 μg$1,58035 days35 days
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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]
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Product Introduction

Bioactivity
Description
Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine.
Chemical Properties
Molecular Weight310.346
FormulaC16H22O6
Cas No.52510-53-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
PBS (pH 7.2): 1 mg/mL (3.22 mM), Sonication is recommended.
DMSO: 50 mg/mL (161.11 mM), Sonication is recommended.
Ethanol: 50 mg/mL (161.11 mM), Sonication is recommended.
DMF: 50 mg/mL (161.11 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMSO/Ethanol/DMF
1mg5mg10mg50mg
1 mM3.2222 mL16.1111 mL32.2221 mL161.1105 mL
DMSO/Ethanol/DMF
1mg5mg10mg50mg
5 mM0.6444 mL3.2222 mL6.4444 mL32.2221 mL
10 mM0.3222 mL1.6111 mL3.2222 mL16.1111 mL
20 mM0.1611 mL0.8056 mL1.6111 mL8.0555 mL
50 mM0.0644 mL0.3222 mL0.6444 mL3.2222 mL
100 mM0.0322 mL0.1611 mL0.3222 mL1.6111 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Keywords

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