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tetranor-PGAM

Name: tetranor-PGAM
Brand: TargetMol
SKU: T38305
Rating: 4.5 (1 reviews)

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Catalog No. T38305Cas No. 52510-53-9

Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine.

tetranor-PGAM

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Catalog No. T38305Cas No. 52510-53-9

Pack Size	Price	USA Warehouse	Global Warehouse
25 μg	$430	35 days	35 days
50 μg	$838	35 days	35 days
100 μg	$1,580	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	310.346
Formula	C₁₆H₂₂O₆
Cas No.	52510-53-9
Smiles	OC(=O)CCCCC(=O)CC[C@H]1C=CC(=O)[C@@H]1CCC(O)=O \|c:12\|

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH 7.2): 1 mg/mL (3.22 mM), Sonication is recommended.

DMSO: 50 mg/mL (161.11 mM), Sonication is recommended.

Ethanol: 50 mg/mL (161.11 mM), Sonication is recommended.

DMF: 50 mg/mL (161.11 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	3.2222 mL	16.1111 mL	32.2221 mL	161.1105 mL

DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
5 mM	0.6444 mL	3.2222 mL	6.4444 mL	32.2221 mL
10 mM	0.3222 mL	1.6111 mL	3.2222 mL	16.1111 mL
20 mM	0.1611 mL	0.8056 mL	1.6111 mL	8.0555 mL
50 mM	0.0644 mL	0.3222 mL	0.6444 mL	3.2222 mL
100 mM	0.0322 mL	0.1611 mL	0.3222 mL	1.6111 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc