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Anti-Ricin B chain Polyclonal Antibody is a Rabbit antibody targeting Ricin B chain. Anti-Ricin B chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $372 | 7-10 days | |
200 μL | $528 | 7-10 days |
Description | Anti-Ricin B chain Polyclonal Antibody is a Rabbit antibody targeting Ricin B chain. Anti-Ricin B chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
Synonyms | RTB, RT B, rRNA N-glycosidase, Ricinus communis(Castor bean), Ricin toxin B chain, Ricin precursor, Ricin chain B, Ricin B lectin, RICI_RICCO, RCA 60 |
Ig Type | IgG |
Reactivity | (predicted:Ricinus communis (Castor Bean plant).) |
Application | |
Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Immunogen | KLH conjugated synthetic peptide: Ricin B chain |
Protein Name | Ricin |
Biology Area | Plant related targets,Regulation |
Function | Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity). |
Molecular Weight | Theoretical: 29 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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