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p67phox Protein, Human, Recombinant

Catalog No. TMPY-03660 Copy Product Info
p67phox Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 30 kDa and the accession number is AAH01606.1.

p67phox Protein, Human, Recombinant

Catalog No. TMPY-03660
Copy Product Info

p67phox Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 30 kDa and the accession number is AAH01606.1.

p67phox Protein, Human, Recombinant
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$687-10 days7-10 days
10 μg$1087-10 days7-10 days
20 μg$1787-10 days7-10 days
50 μg$3597-10 days7-10 days
100 μg$6967-10 days7-10 days
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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Biological Activity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
p67phox Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 30 kDa and the accession number is AAH01606.1.
Species
Human
Expression System
Baculovirus Insect Cells
TagTag Free
Accession NumberAAH01606.1
Synonyms
P67-PHOX,P67PHOX,NOXA2,neutrophil cytosolic factor 2,NCF-2
Construction
A DNA sequence encoding the human NCF2 (AAH01606.1) (Met1-Val526) was expressed and purified with two additional amino acids (Gly & Pro) at the N-terminus. Predicted N terminal: Gly
Protein Purity
> 85 % as determined by SDS-PAGE
Molecular Weight30 kDa (predicted); 60 kDa (reducing condition, due to glycosylation)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 300 mM NaCl, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background
NCF2 (Neutrophil Cytosolic Factor 2, also known as NCF-2 and p67phox) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. NCF2 belongs to the NCF2/NOXA1 family. NCF2, NCF1, and a membrane-bound cytochrome b558 are required for activation of the latent NADPH oxidase. Mutations in the NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

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