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Anti-DKK2 Polyclonal Antibody is a Rabbit antibody targeting DKK2. Anti-DKK2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $374 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-DKK2 Polyclonal Antibody is a Rabbit antibody targeting DKK2. Anti-DKK2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA. |
Synonyms | hDkk-2, Dkk-2, DKK2, Dickkopf-related protein 2, Dickkopf-2 |
Ig Type | IgG |
Reactivity | (predicted:Human,Mouse,Rat,Chicken,Dog,Pig,Horse,Rabbit,Sheep) |
Application | |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted. |
Tissue Specificity | Expressed in heart, brain, skeletal muscle and lung. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Immunogen | KLH conjugated synthetic peptide: human DKK2 |
Antigen Species | Human |
Gene Name | DKK2 |
Gene ID | |
Protein Name | Dickkopf-related protein 2 |
Uniprot ID | |
Biology Area | Secreted |
Function | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
Molecular Weight | Theoretical: 25 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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