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Anti-KLK10 Polyclonal Antibody
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Catalog No. TMAB-01029
Alias PRSSL1, Protease Serine-Like 1, Normal Epithelial Cell-Specific 1, NES1, KLK10, Kallikrein-10
Anti-KLK10 Polyclonal Antibody is a Rabbit antibody targeting KLK10. Anti-KLK10 Polyclonal Antibody can be used in WB.
Anti-KLK10 Polyclonal Antibody
Anti-KLK10 Polyclonal Antibody
😃Good
Catalog No. TMAB-01029Alias PRSSL1, Protease Serine-Like 1, Normal Epithelial Cell-Specific 1, NES1, KLK10, Kallikrein-10
Anti-KLK10 Polyclonal Antibody is a Rabbit antibody targeting KLK10. Anti-KLK10 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-KLK10 Polyclonal Antibody is a Rabbit antibody targeting KLK10. Anti-KLK10 Polyclonal Antibody can be used in WB. |
| Alias | PRSSL1, Protease Serine-Like 1, Normal Epithelial Cell-Specific 1, NES1, KLK10, Kallikrein-10 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Cow) |
| Verified Activity | 1. Sample: MCF-7 (Human) Cell Lysate at 30 μg Primary: Anti-NES/Kallikrein 10 (TMAB-01029) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa 2. Sample: DU145 (Human) Cell Lysate at 30 μg Primary: Anti-NES/Kallikrein 10 (TMAB-01029) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Kallikrein 10 is a trypsin-like serine proteinase. Originally described from a subtractive library looking for genes that were down-regulated in breast cancer, kallikrein 10 was thought to be epithelial cell specific. Kallikrein 10 is reported to be up regulated in pancreatic cancer and ovarian cancer, but down regulated in testicular cancer and breast cancer, perhaps due to differential hormonal regulation, or tissue specificities. Breast cancer patients that had elevated kallikrein 10 had a worse prognosis, leading to speculation that kallikrein 10 might be protective in breast cancer, similar to the argument put forth for kallikrein 3 in prostate cancer. Kallikrein 10 is found in high levels in the pancreas and in lower levels in the tonsils, esophagus, skin, brain, testis and ovary. Biological fluids (breast milk, serum, seminal plasma, urine) contain kallikrein 10, the highest levels found in milk. The cerebral spinal fluid (CSF) contains Kallikrein 10, and was reported to be elevated in patients with Alzheimer’s disease. Endogenous inhibitors include kallistatin, protein-C inhibitor and 1-proteinase inhibitor, although Kallikrein 10 can be found complexed to a number of different proteinase inhibitors. |
| Immunogen | KLH conjugated synthetic peptide: human KLK10 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID |
| Molecular Weight | Theoretical: 31 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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