Shopping Cart

Your shopping cart is currently empty

PNU-100440

Name: PNU-100440
Brand: TargetMol
SKU: T19645
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T19645Cas No. 168828-82-8

PNU-100440 is a biologically active compound. It is an intermediate in the synthesis of linezolid dimers, an impurity of the antibacterial agent Linezolid.

PNU-100440

Copy Product Info

😃Good

Purity: 99.09%

Catalog No. T19645Cas No. 168828-82-8

PNU-100440 is a biologically active compound. It is an intermediate in the synthesis of linezolid dimers, an impurity of the antibacterial agent Linezolid.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.09%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

PNU-100440 AI Summary

PNU-100440 exhibits antimicrobial activity against various bacterial strains, including Mycobacterium vaccae, Pseudomonas aeruginosa (both mutant and wild type), Enterococcus faecalis, Staphylococcus aureus, Micrococcus luteus, and Bacillus subtilis. When tested at a concentration of 2 mM using the agar diffusion method, it demonstrates inhibition zones that range from 0.0 mm to 43.0 mm, indicating varying degrees of effectiveness against these microorganisms..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

PNU-100440 is a biologically active compound. It is an intermediate in the synthesis of linezolid dimers, an impurity of the antibacterial agent Linezolid.

Chemical Properties

Molecular Weight	296.29
Formula	C₁₄H₁₇FN₂O₄
Cas No.	168828-82-8
Smiles	OC[C@H]1CN(C(=O)O1)C1=CC(F)=C(C=C1)N1CCOCC1
Relative Density.	1.362g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (202.5 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3751 mL	16.8754 mL	33.7507 mL	168.7536 mL
5 mM	0.6750 mL	3.3751 mL	6.7501 mL	33.7507 mL
10 mM	0.3375 mL	1.6875 mL	3.3751 mL	16.8754 mL
20 mM	0.1688 mL	0.8438 mL	1.6875 mL	8.4377 mL
50 mM	0.0675 mL	0.3375 mL	0.6750 mL	3.3751 mL
100 mM	0.0338 mL	0.1688 mL	0.3375 mL	1.6875 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc