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TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant
(Synonyms: ZTNFR9, Tumor necrosis factor receptor superfamily member 10B, TRICKB, TRICK2B, TRICK2A, TRICK2, TRAIL-R2, TRAILR2, TRAIL receptor 2, TNFRSF10B, TNF-related apoptosis-inducing ligand receptor 2, KILLER/DR5, KILLER, DR5, Death receptor 5, CD262) Copy Product InfoSynonyms: ZTNFR9, Tumor necrosis factor receptor superfamily member 10B, TRICKB, TRICK2B, TRICK2A, TRICK2, TRAIL-R2, TRAILR2, TRAIL receptor 2, TNFRSF10B, TNF-related apoptosis-inducing ligand receptor 2, KILLER/DR5, KILLER, DR5, Death receptor 5, CD262
Catalog No. TMPS-00158 Copy Product Info
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant is expressed in E. coli. The accession number is O14763.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $91 | 7-10 days | 7-10 days | |
| 10 µg | $147 | 7-10 days | 7-10 days | |
| 20 µg | $213 | 7-10 days | 7-10 days | |
| 50 µg | $356 | 7-10 days | 7-10 days | |
| 100 µg | $553 | 7-10 days | 7-10 days | |
| 200 µg | $866 | 7-10 days | 7-10 days | |
| 500 µg | $1,560 | 7-10 days | 7-10 days | |
| 1 mg | $2,460 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Fully biologically active when compared to standard. rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/ml) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed. |
| Description | TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant is expressed in E. coli. The accession number is O14763. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | O14763 |
| Construction | Glu52-Ser183 |
| Protein Purity | > 97% as determined by SDS-PAGE; > 97% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4. |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. |
| Synonyms | ZTNFR9, Tumor necrosis factor receptor superfamily member 10B, TRICKB, TRICK2B, TRICK2A, TRICK2, TRAIL-R2, TRAILR2, TRAIL receptor 2, TNFRSF10B, TNF-related apoptosis-inducing ligand receptor 2, KILLER/DR5, KILLER, DR5, Death receptor 5, CD262 |
| Research Background | Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.2 TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients. |
| Molecular Weight | 14.8 kDa (Predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
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Related Tags: TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant chemical structure | TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant molecular weight
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