Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Name: Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
Brand: TargetMol
SKU: TMPK-00720
Rating: 4.5 (1 reviews)

(Synonyms: SIGLEC5, OB-BP2, OBBP2, CD33L2, CD33 antigen-like 2, CD170) Copy Product Info

Synonyms: SIGLEC5, OB-BP2, OBBP2, CD33L2, CD33 antigen-like 2, CD170

Catalog No. TMPK-00720 Copy Product Info

Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity.

Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Pack Size	Price	USA Stock	Global Stock
5 µg	$91	7-10 days	7-10 days
10 µg	$148	7-10 days	7-10 days
20 µg	$245	7-10 days	7-10 days
50 µg	$483	7-10 days	7-10 days
100 µg	$813	7-10 days	7-10 days
200 µg	$1,470	7-10 days	7-10 days
500 µg	$3,250	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	O15389
Construction	Glu17-Thr434
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SIGLEC5, OB-BP2, OBBP2, CD33L2, CD33 antigen-like 2, CD170
Research Background	Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity.

Chemical Properties

Molecular Weight

73.1 kDa (predicted). Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Recombinant Proteins

Keywords

SIGLEC-5SIGLEC 5OBBP-2OBBP 2CD-170CD 170

Related Tags: Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated chemical structure | Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated molecular weight