CD44 Protein, Cynomolgus, Recombinant (His)

Name: CD44 Protein, Cynomolgus, Recombinant (His)
Brand: TargetMol
SKU: TMPK-00518
Rating: 4.5 (1 reviews)

(Synonyms: PGP-I, MIC4, MDU3, MDU2, MC56, LHR, IN, HUTCH-I, HCELL, Epican, ECMR-III, CSPG8, CDw44, CD44) Copy Product Info

Synonyms: PGP-I, MIC4, MDU3, MDU2, MC56, LHR, IN, HUTCH-I, HCELL, Epican, ECMR-III, CSPG8, CDw44, CD44

Catalog No. TMPK-00518 Copy Product Info

CD44 is a hyaluronan binding cell surface signal transducing receptor that influences motility, cell survival and proliferation as well as the formation of tumor microenvironment. CD44 contains two variable regions encoded by variable exons. Alternative splicing, which is often deregulated in cancer, can produce various isoforms of CD44 with properties that may have different tissue specific effects and therefore even diverse effects on cancer progression

CD44 Protein, Cynomolgus, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$58	7-10 days	7-10 days
10 µg	$92	7-10 days	7-10 days
20 µg	$148	7-10 days	7-10 days
50 µg	$289	7-10 days	7-10 days
100 µg	$487	7-10 days	7-10 days
200 µg	$883	7-10 days	7-10 days
500 µg	$1,950	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Cynomolgus CD44, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD44 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA.
Description	CD44 is a hyaluronan binding cell surface signal transducing receptor that influences motility, cell survival and proliferation as well as the formation of tumor microenvironment. CD44 contains two variable regions encoded by variable exons. Alternative splicing, which is often deregulated in cancer, can produce various isoforms of CD44 with properties that may have different tissue specific effects and therefore even diverse effects on cancer progression
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	A0A2K5VJE0
Construction	Gln21-Pro220 & Gln387-Ala428
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	PGP-I, MIC4, MDU3, MDU2, MC56, LHR, IN, HUTCH-I, HCELL, Epican, ECMR-III, CSPG8, CDw44, CD44
Research Background	CD44 is a hyaluronan binding cell surface signal transducing receptor that influences motility, cell survival and proliferation as well as the formation of tumor microenvironment. CD44 contains two variable regions encoded by variable exons. Alternative splicing, which is often deregulated in cancer, can produce various isoforms of CD44 with properties that may have different tissue specific effects and therefore even diverse effects on cancer progression

Chemical Properties

Molecular Weight

27.77 kDa (predicted). Due to glycosylation, the protein migrates to 45-70 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.