CXCL13/BCA-1 Protein, Human, Recombinant

Name: CXCL13/BCA-1 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-04887
Rating: 4.5 (1 reviews)

(Synonyms: SCYB13, chemokine (C-X-C motif) ligand 13, BLR1L, BLC, BCA-1, BCA1, ANGIE2, ANGIE) Copy Product Info

Synonyms: SCYB13, chemokine (C-X-C motif) ligand 13, BLR1L, BLC, BCA-1, BCA1, ANGIE2, ANGIE

Catalog No. TMPY-04887 Copy Product Info

Purity: 97.9%

BCA-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is O43927.

CXCL13/BCA-1 Protein, Human, Recombinant

Pack Size	Price	USA Stock	Global Stock
5 µg	$80	7-10 days	7-10 days
10 µg	$129	7-10 days	7-10 days
20 µg	$212	-	In Stock
50 µg	$359	7-10 days	7-10 days
100 µg	$539	7-10 days	7-10 days
200 µg	$953	7-10 days	7-10 days
500 µg	$2,020	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:97.9%

Appearance:Lyophilized powder

Color:White

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	BCA-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is O43927.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	O43927
Construction	A DNA sequence encoding the human CXCL13 (NP_006410.1) (Val23-Arg94) was expressed with an initial Met. Predicted N terminal: Met
Protein Purity	> 95 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 0.5 M NaCl, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	SCYB13, chemokine (C-X-C motif) ligand 13, BLR1L, BLC, BCA-1, BCA1, ANGIE2, ANGIE
Research Background	The chemokine CXCL13, also known as BCA-1 (B-cell-attracting chemokine-1) or BLC (B-lymphocyte chemoattractant), which belongs to the CXC chemokine family. CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. CXCL13 is known to dictate homing and motility of B cells in lymphoid tissue and has been implicated in the formation of ectopic lymphoid tissue in chronic inflammation. It involves in B-cell compartmental homing within secondary lymphoid organs and recently implicated in the pathogenesis of inflammatory and malignant lymphocyte-mediated diseases. In Primary central nervous system lymphoma (PCNSL), expression of BCA-1 by malignant lymphocytes and vascular endothelium may influence tumor development and localization to central nervous system (CNS). In T-lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the T-cell. CXCL13 expression may also provide an additional useful tool for the diagnosis of Angioimmunoblastic T-cell lymphoma (AITL).

Chemical Properties

Molecular Weight

8.8 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.