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Anti-MAPT Antibody (2Z110)

(Synonyms: TAU and MAPT, Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL) Copy Product Info
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Synonyms: TAU and MAPT, Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL

Catalog No. TMAH-00735 Copy Product Info
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Anti-MAPT Antibody (2Z110) is an antibody targeting MAPT. Anti-MAPT Antibody (2Z110) can be used in ELISA,IHC.
Anti-MAPT Antibody
(2Z110)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MAPT Antibody (2Z110) is an antibody targeting MAPT. Anti-MAPT Antibody (2Z110) can be used in ELISA,IHC.
SynonymsTAU and MAPT, Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL
Ig Type
Rabbit IgG
Clone
2Z110
Reactivity
Human
Application
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted.
Tissue SpecificityExpressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundPromotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human Tau
Antigen Species
Human
Gene Name
MAPT
Gene ID
Uniprot ID
Biology Area
Neuroscience, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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