Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-NPC2 Monoclonal Antibody (Synonyms: NPC intracellular cholesterol transporter 2, Niemann-Pick disease type...)
Catalog No. TMAZ-0065 Copy Product Info
🥰Excellent
Anti-NPC2 Monoclonal Antibody is a humanized rabbit antibody targeting NPC2. Anti-NPC2 Monoclonal Antibody can be used in ELISA,FCM.
Anti-NPC2 Monoclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAZ-0065
Synonyms NPC intracellular cholesterol transporter 2, Niemann-Pick disease type C2 protein, Human epididymis-specific protein 1, Epididymal secretory protein E1
Anti-NPC2 Monoclonal Antibody is a humanized rabbit antibody targeting NPC2. Anti-NPC2 Monoclonal Antibody can be used in ELISA,FCM.
Anti-NPC2 Monoclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-NPC2 Monoclonal Antibody is a humanized rabbit antibody targeting NPC2. Anti-NPC2 Monoclonal Antibody can be used in ELISA,FCM. |
| Synonyms | NPC intracellular cholesterol transporter 2, Niemann-Pick disease type C2 protein, Human epididymis-specific protein 1, Epididymal secretory protein E1 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of NPC2 overexpressed 476F cells with TMAZ-0065, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of NPC2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment (PubMed: 11125141, PubMed: 15937921, PubMed: 17018531, PubMed: 18772377, PubMed: 29580834). Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1 (PubMed: 17018531, PubMed: 18772377, PubMed: 27238017). May bind and mobilize cholesterol that is associated with membranes (PubMed: 18823126). NPC2 binds cholesterol with a 1: 1 stoichiometry (PubMed: 17018531). Can bind a variety of sterols, including lathosterol, desmosterol and the plant sterols stigmasterol and beta-sitosterol (PubMed: 17018531). The secreted form of NCP2 regulates biliary cholesterol secretion via stimulation of ABCG5/ABCG8-mediated cholesterol transport (By similarity) |
| Conjucates | Unconjugated |
| Others Formats | Biotin |
| Antibody Types Available | 2 |
| Immunogen | NPC2 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-NPC2 Monoclonal Antibody | purchase Anti-NPC2 Monoclonal Antibody | Anti-NPC2 Monoclonal Antibody cost | order Anti-NPC2 Monoclonal Antibody | Anti-NPC2 Monoclonal Antibody molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.