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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG8-azide is a PEG-based linker for PROTACs that connects two essential ligands, pivotal in forming PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker; one ligand targets an E3 ubiquitin ligase, while the other targets the desired protein. Leveraging the intracellular ubiquitin-proteasome system, PROTACs enable the selective degradation of target proteins. |
Molecular Weight | 409.48 |
Formula | C17H35N3O8 |
Cas No. | 869718-80-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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