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L-Tyrosine

Name: L-Tyrosine
Brand: TargetMol
SKU: T0493
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0493Cas No. 60-18-4

Alias Tyrosine, P-Tyrosine, L-p-Tyrosine, (S)-Tyrosine

L-Tyrosine ((S)-Tyrosine) is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine, considered a non-essential amino acid. L-Tyrosine(L-p-Tyrosine) is the levorotatory isomer of the aromatic amino acid tyrosine.

L-Tyrosine

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Purity: 99.82%

Catalog No. T0493Alias Tyrosine, P-Tyrosine, L-p-Tyrosine, (S)-TyrosineCas No. 60-18-4

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$30	In Stock	In Stock
100 mg	$38	In Stock	In Stock
500 mg	$76	In Stock	In Stock
1 g	$109	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.82%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	L-Tyrosine ((S)-Tyrosine) is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine, considered a non-essential amino acid. L-Tyrosine(L-p-Tyrosine) is the levorotatory isomer of the aromatic amino acid tyrosine.
In vitro	L-tyrosine in vitro inhibits citrate synthase activity in the posterior cortex. Succinate dehydrogenase activity is increased in the posterior cortex, hippocampus, striatum and liver. Complex I activity is inhibited in the hippocampus, complex II activity is also inhibited in the hippocampus and in the posterior cortex and liver, complex II–III activity is not altered by L-tyrosine and complex IV activity decreased in the posterior cortex[1].
In vivo	Acute administration of L-tyrosine inhibits malate dehydrogenase and complex II, II–III and IV of the mitochondrial respiratory chain activity in the posterior cortex and liver of rats. The succinate dehydrogenase enzyme and complex I activity are inhibited in the posterior cortex and increased in the striatum[1].
Synonyms	Tyrosine, P-Tyrosine, L-p-Tyrosine, (S)-Tyrosine

Chemical Properties

Molecular Weight	181.19
Formula	C₉H₁₁NO₃
Cas No.	60-18-4
Smiles	C([C@@H](C(O)=O)N)C1=CC=C(O)C=C1
Relative Density.	1.34

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

0.1 M HCl: 10 mg/mL (55.19 mM), Sonication is recommended.

DMSO: Insoluble

H2O: Insoluble

Solution Preparation Table

0.1 M HCl

	1mg	5mg	10mg	50mg
1 mM	5.5191 mL	27.5953 mL	55.1907 mL	275.9534 mL
5 mM	1.1038 mL	5.5191 mL	11.0381 mL	55.1907 mL
10 mM	0.5519 mL	2.7595 mL	5.5191 mL	27.5953 mL
20 mM	0.2760 mL	1.3798 mL	2.7595 mL	13.7977 mL
50 mM	0.1104 mL	0.5519 mL	1.1038 mL	5.5191 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc