SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin homologue, Small Ubiquitin-Like Modifier 1 (SUMO-1). The conjugation of ubiquitin requires the activities of ubiquitin-activating (E1) and conjugating (E2) enzymes. It is suggested that UBC9 might play a role in DNA repair and perhaps even in aging.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 53.00 | |
50 μg | 5 days | $ 129.00 | |
500 μg | 5 days | $ 1,390.00 | |
1 mg | 5 days | $ 1,980.00 |
Description | SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin homologue, Small Ubiquitin-Like Modifier 1 (SUMO-1). The conjugation of ubiquitin requires the activities of ubiquitin-activating (E1) and conjugating (E2) enzymes. It is suggested that UBC9 might play a role in DNA repair and perhaps even in aging. |
Species | Human |
Expression System | E. coli |
Tag | N-GST |
Accession Number | P63279 |
Synonyms | SUMO-Protein Ligase, Ubiquitin-Conjugating Enzyme E2 I, p18, UBC9, Ubiquitin Carrier Protein I, SUMO-Conjugating Enzyme UBC9, Ubiquitin-Protein Ligase I, UBE2I, UBCE9, Ubiquitin Carrier Protein 9 |
Amino Acid | Met1-Ser158 |
Construction | Recombinant Human Ubiquitin-Conjugating Enzyme E2 I is produced by our E.coli expression system and the target gene encoding Met1-Ser158 is expressed with a GST tag at the N-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 40 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, pH 7.5. |
Stability & Storage |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Shipping |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Research Background | SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin homologue, Small Ubiquitin-Like Modifier 1 (SUMO-1). The conjugation of ubiquitin requires the activities of ubiquitin-activating (E1) and conjugating (E2) enzymes. It is suggested that UBC9 might play a role in DNA repair and perhaps even in aging. |
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UBE2I Protein, Human, Recombinant (GST) SUMO-Protein Ligase Ubiquitin-Conjugating Enzyme E2 I p18 UBC-9 UBC9 Ubiquitin Carrier Protein I SUMO-Conjugating Enzyme UBC9 UBCE-9 Ubiquitin-Protein Ligase I UBE2I UBCE 9 UBCE9 UBC 9 Ubiquitin Carrier Protein 9 recombinant recombinant-proteins proteins protein