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Anti-interferon alpha 5/IFNA5 Antibody (1G423) is a Rabbit antibody targeting interferon alpha 5/IFNA5. Anti-interferon alpha 5/IFNA5 Antibody (1G423) can be used in ELISA.
Description | Anti-interferon alpha 5/IFNA5 Antibody (1G423) is a Rabbit antibody targeting interferon alpha 5/IFNA5. Anti-interferon alpha 5/IFNA5 Antibody (1G423) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1G423 |
Reactivity | Rat |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat IFNA5 / IFNaG (rR IFNA5 / IFNaG; TMPY-03130; XP_001076062.1; Met1-Glu189). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation. |
Conjucates | Unconjugated |
Immunogen | Recombinant Rat IFNA5 / IFNaG Protein (TMPY-03130) |
Antigen Species | Rat |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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