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Spliceostatin A (GMP) refers to the GMP grade reagents of Spliceostatin A. Spliceostatin A is an anticancer agent and splicing inhibitor that inhibits the splicing mechanism of the spliceosome and inhibits mitotic clonal expansion and adipogenesis.Spliceostatin A induces cell cycle arrest in the G1 and G2/M phases, and induces apoptosis.


| Description | Spliceostatin A (GMP) refers to the GMP grade reagents of Spliceostatin A. Spliceostatin A is an anticancer agent and splicing inhibitor that inhibits the splicing mechanism of the spliceosome and inhibits mitotic clonal expansion and adipogenesis.Spliceostatin A induces cell cycle arrest in the G1 and G2/M phases, and induces apoptosis. |
| In vitro | Spliceostatin A (0, 2.5 nM, 5 nM, 10 nM, and 20 nM; 0, 6 h, 12 h, and 24 h) increases apoptosis in chronic lymphocytic leukemia (CLL) cells[1]. |
| Molecular Weight | 521.643 |
| Formula | C28H43NO8 |
| Cas No. | 391611-36-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |

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