N-(5-Hydroxypentyl)maleimide

Name: N-(5-Hydroxypentyl)maleimide
Brand: TargetMol
SKU: T18369
Rating: 4.5 (1 reviews)

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Catalog No. T18369Cas No. 180608-78-0

N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in synthesizing antibody-drug conjugates (ADCs) and is essential in producing the ADC compound Gemcitabine-O-Si(di-iso)-O-Mc [1].

N-(5-Hydroxypentyl)maleimide

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Catalog No. T18369Cas No. 180608-78-0

N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in synthesizing antibody-drug conjugates (ADCs) and is essential in producing the ADC compound Gemcitabine-O-Si(di-iso)-O-Mc [1].

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$42	5 days	5 days
5 mg	$65	5 days	5 days
10 mg	$93	5 days	5 days
25 mg	$153	5 days	5 days
100 mg	Inquiry	5 days	5 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in synthesizing antibody-drug conjugates (ADCs) and is essential in producing the ADC compound Gemcitabine-O-Si(di-iso)-O-Mc [1].
In vitro	Antibody-drug conjugates (ADCs) consist of an antibody connected to a cytotoxin via a linker. [1].

Chemical Properties

Molecular Weight	183.2
Formula	C₉H₁₃NO₃
Cas No.	180608-78-0
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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