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Anti-CTH Polyclonal Antibody
(Synonyms: γ-Cystathionase, Gamma-Cystathionase, Cysteine-Protein Sulfhydrase, Cystathionine γ-Lyase, Cystathionine Gamma-Lyase, CTH) Copy Product Info
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Synonyms: γ-Cystathionase, Gamma-Cystathionase, Cysteine-Protein Sulfhydrase, Cystathionine γ-Lyase, Cystathionine Gamma-Lyase, CTH
Catalog No. TMAB-00490 Copy Product Info
🥰Excellent
Anti-CTH Polyclonal Antibody is a Rabbit antibody targeting CTH. Anti-CTH Polyclonal Antibody can be used in FCM,WB.
Anti-CTH Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CTH Polyclonal Antibody is a Rabbit antibody targeting CTH. Anti-CTH Polyclonal Antibody can be used in FCM,WB. |
| Synonyms | γ-Cystathionase, Gamma-Cystathionase, Cysteine-Protein Sulfhydrase, Cystathionine γ-Lyase, Cystathionine Gamma-Lyase, CTH |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Cow,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 2ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion. |
| Immunogen | KLH conjugated synthetic peptide: human CTH/CSE/Cystathionase |
| Antigen Species | Human |
| Gene Name | CTH |
| Gene ID | |
| Protein Name | Cystathionine gamma-lyase |
| Uniprot ID | |
| Biology Area | Amino acid metabolism,Amino Acids |
| Function | Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into –SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function. |
| Molecular Weight | Theoretical: 45 kDa. Actual: 45 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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