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Anti-CALML5 Antibody (4X239)
😃Good
Catalog No. TMAY-02055
Alias CLSP, calmodulin like 5
Anti-CALML5 Antibody (4X239) is a Rabbit antibody targeting CALML5. Anti-CALML5 Antibody (4X239) can be used in IHC-P.
Anti-CALML5 Antibody (4X239)
Anti-CALML5 Antibody (4X239)
😃Good
Catalog No. TMAY-02055Alias CLSP, calmodulin like 5
Anti-CALML5 Antibody (4X239) is a Rabbit antibody targeting CALML5. Anti-CALML5 Antibody (4X239) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CALML5 Antibody (4X239) is a Rabbit antibody targeting CALML5. Anti-CALML5 Antibody (4X239) can be used in IHC-P. |
| Alias | CLSP, calmodulin like 5 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4X239 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human CALML5 in human skin with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to epithelium. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CALML5 (rh CALML5; TMPY-01953; AAH39172.1; Met1-Glu146). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CALML5 protein (TMPY-01953) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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