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Anti-VISTA Antibody (7V405) is a Mouse antibody targeting VISTA. Anti-VISTA Antibody (7V405) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-VISTA Antibody (7V405) is a Mouse antibody targeting VISTA. Anti-VISTA Antibody (7V405) can be used in IHC-P. |
Alias | V-set immunoregulatory receptor, VISTA, SISP1, PP2135, PD-1H, GI24, DD1α, DD1alpha, C10orf54, B7-H5, B7H5 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 7V405 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human C10orf54 in human kidney with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. |
Application | IHC-P |
Recommended Dose | IHC-P: 1:30-1:100 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. VSIR, or V-set immunoregulatory receptor, could be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an inhibitory immune-checkpoint molecule that suppresses CD4+ and CD8+ T cell activation when expressed on antigen-presenting cells. VSIR is broadly expressed in the spleen, bone marrow, and other tissues. Diseases associated with VSIR include Ichthyosis, Congenital, Autosomal Recessive 6, and Monckeberg Arteriosclerosis. An important paralog of this gene is VSIG8. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human VISTA/GI24/B7-H5 Protein (TMPY-03219) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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