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CX3CR1 Protein-VLP, Human, Recombinant (Flag & Strep)
(Synonyms: V28, GPRV28, GPR13, CX3CR1, CMKDR1, CMKBRL1, CCRL1) Copy Product InfoSynonyms: V28, GPRV28, GPR13, CX3CR1, CMKDR1, CMKBRL1, CCRL1
Catalog No. TMPY-07102 Copy Product Info
CX3CR1 Protein-VLP, Human, Recombinant (Flag & Strep) is expressed in HEK293 Cells. The accession number is P49238.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $276 | - | In Stock | |
| 10 µg | $460 | - | In Stock | |
| 20 µg | $773 | 7-10 days | 7-10 days | |
| 50 µg | $1,180 | 7-10 days | 7-10 days | |
| 100 µg | $1,870 | 7-10 days | 7-10 days | |
| 200 µg | $2,800 | 7-10 days | 7-10 days | |
| 500 µg | $6,630 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized CX3CR1 Protein-VLP, Human, Recombinant (Flag & Strep)) (Cat#TMPY-07102) at 5 μg/mL (100 μL/well) can bind Anti-CX3CR1 Monoclonal antibody, heavy chain antibody, Human IgG1, the EC50 is 0.5-5 ng/mL. |
| Description | CX3CR1 Protein-VLP, Human, Recombinant (Flag & Strep) is expressed in HEK293 Cells. The accession number is P49238. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-Flag, C-Strep |
| Accession Number | P49238 |
| Construction | A DNA sequence encoding the Human CX3CR1-VLP (P49238) (Met1-Leu315,thermostabilizing mutations) was expressed, with a Flag tag at the N-terminus, and a strep tag at the C-terminus. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as sterile 50 mM Hepes, 150 mM NaCl, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Synonyms | V28, GPRV28, GPR13, CX3CR1, CMKDR1, CMKBRL1, CCRL1 |
| Research Background | The CX3C chemokine axis consists of fractalkine (CX3CL1) and its receptor (CX3CR1); these are expressed by neurons and microglia respectively, and are known to modulate microglial activation. Neuronal Cx3cr1 may impact Alzheimer's disease-like pathology by modulating conformational state-dependent amyloid-beta-induced synaptotoxicity. Microglial cells participate in brain development and influence neuronal loss and synaptic maturation. Fractalkine is an important neuronal chemokine whose expression increases during development and that can influence microglia function via the fractalkine receptor, CX3CR1. Mice lacking Cx3cr1 show a variety of neuronal defects thought to be the result of deficient microglia function. Knockout of the microglial chemokine receptor Cx3cr1 to prevent neuron loss. |
| Molecular Weight | 40.4 kDa (predicted) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
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Related Tags: CX3CR1 Protein-VLP, Human, Recombinant (Flag & Strep) chemical structure | CX3CR1 Protein-VLP, Human, Recombinant (Flag & Strep) molecular weight
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