α-Conotoxin PIA TFA

Name: α-Conotoxin PIA TFA
Brand: TargetMol
SKU: T75876
Price: 322 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T75876

α-Conotoxin PIA TFA is an nAChR (nicotinic acetylcholine receptor) antagonist that primarily targets nAChR subtypes containing α6 and α3 subunits, exhibiting significantly higher selectivity for α6/α3β2β3 nAChR than α3β2 nAChR, and may be used for Parkinson's disease and schizophrenia.

α-Conotoxin PIA TFA

🥰Excellent

Purity: 98.81%

Catalog No. T75876

Pack Size	Price	Availability
1 mg	$322	In Stock
5 mg	$783	In Stock
10 mg	$1,090	In Stock
25 mg	$1,620	In Stock
50 mg	$2,190	In Stock

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Purity:98.81%

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COA HPLC MS

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	2095.3
Formula	C₈₁H₁₂₆F₃N₂₇O₂₇S₄
Smiles	O=C1N2[C@](CCC2)([H])C(N[C@H](C(N[C@@](C(N[C@@H](CSSC[C@]3([H])NC([C@H](CSSC[C@@](NC([C@@H](NC([C@@]4([H])N(CCC4)C([C@@H](NC([C@@H](NC3=O)CO)=O)CC(N)=O)=O)=O)C(C)C)=O)([H])C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@H]1CC(N)=O)=O)CC5=CN=CN5)=O)C(C)C)=O)([H])[C@H](O)C)=O)NC([C@H]6N(CCC6)C([C@H](CC(O)=O)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)C(N)=O)=O)([H])[C@@H](C)CC)=O)CCC(N)=O)=O.O=C(C(F)(F)F)O
Color	White
Appearance	Solid
Sequence	Arg-Asp-Pro-Cys-Cys-Ser-Asn-Pro-Val-Cys-Thr-Val-His-Asn-Pro-Gln-Ile-Cys-NH2 (Disulfide bridge:Cys4-Cys10;Cys5-Cys18)
Sequence Short	RDPCCSNPVCTVHNPQIC-NH2 (Disulfide bridge:Cys4-Cys10;Cys5-Cys18)

Storage & Solubility Information

Storage	keep away from moisture \| Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: ≥ 200 mg/mL, Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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