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Anti-CPLX2 Antibody (3Z959)
(Synonyms: Hfb1, CPX-2, CPX2, complexin 2, 921-L) Copy Product Info
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Synonyms: Hfb1, CPX-2, CPX2, complexin 2, 921-L
Catalog No. TMAY-02146 Copy Product Info
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Anti-CPLX2 Antibody (3Z959) is a Rabbit antibody targeting CPLX2. Anti-CPLX2 Antibody (3Z959) can be used in FCM,ICC/IF.
Anti-CPLX2 Antibody
(3Z959)
(3Z959)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CPLX2 Antibody (3Z959) is a Rabbit antibody targeting CPLX2. Anti-CPLX2 Antibody (3Z959) can be used in FCM,ICC/IF. |
| Synonyms | Hfb1, CPX-2, CPX2, complexin 2, 921-L |
| Ig Type | Rabbit IgG |
| Clone | 3Z959 |
| Reactivity | Human |
| Specificity | Human CPLX2 |
| Application | |
| Recommended Dose | ICC-IF: 1:20-1:100; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Complexin-2 / CPLX2 (rh Complexin-2 / CPLX2; TMPY-02025; Q6PUV4-1; Asp2-Lys134). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Complexin-2 (CPLX2), a member of the complexin/synaphin family, is a soluble pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals. Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Complexins are unable to bind to monomeric SNARE proteins but bind with high affinity to ternary SNARE complexes and with lower affinity to target SNARE complexes. Complexin 1 (CX1) and complexin 2 (CX2) are presynaptic proteins that modulate neurotransmitter release and are used as markers of inhibitory and excitatory synapses, respectively. CPLX2 is localized in pre-synaptic terminals in mature brain. The G71-P89 region of CPLX2 is essential and sufficient for preferential axonal distribution. CPLX2 participates in the Ca(2+)-sensitive regulatory pathway for zymogen granule exocytosis. Complexin-2 is a key player in normal neurological function, and its downregulation could lead to changes in neurotransmitter release sufficient to cause significant behavioural abnormalities such as depression. It is involved in synaptogenesis and the modulation of neurotransmitter release. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Complexin-2 / CPLX2 Protein (TMPY-02025) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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