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HPV16 E7 (86-93) acetate
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Catalog No. TP1554L
Alias HPV16 E7 (86-93) acetate(160212-93-1 Free base)
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.
HPV16 E7 (86-93) acetate
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Purity: 96.9100%
Catalog No. TP1554LAlias HPV16 E7 (86-93) acetate(160212-93-1 Free base)
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $54 | - | In Stock | |
| 5 mg | $111 | - | In Stock | |
| 10 mg | $158 | - | In Stock | |
| 25 mg | $266 | - | In Stock | |
| 50 mg | $371 | - | In Stock | |
| 100 mg | $517 | - | In Stock | |
| 200 mg | $697 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:96.9100%
Appearance:Solid
Color:White
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| Description | HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas. |
| In vitro | HPV16 E7 peptide-loaded autologous dendritic cells stimulate a specific cytotoxic CD8+ T-cell response[1]. HPV16 E7 (86-93) acetate specific T cells expand upon in vitro stimulation with cognate peptide-pulsed dendritic cells. HPV16 E7 (86-93) acetate specific T cells are reactive against peptide-pulsed targets. HPV16 E7 (86-93) acetate specific E711-20 T cells are reactive against HPV16 E7 expressing CaSki cell line. Precursor T cells specific for HPV16 E7 (86-93) acetate differentiates into HPV specific effector cells in vitro[2]. |
| In vivo | HPV16 E7 (86-93) acetate in IVS culture has specific T cell expansion without recognizing naturally HPV16 E7 expressing cell line CaSki. HPV16 E7 (86-93) acetate has similar observations in transgenic mice. HPV16 E7 (86-93) acetate induces cytotoxic T lymphocyte responses when loaded on the antigen presenting HLA class I molecules[2]. |
| Synonyms | HPV16 E7 (86-93) acetate(160212-93-1 Free base) |
| Molecular Weight | 875.08 |
| Formula | C39H70N8O12S |
| Smiles | C[C@@H](O)[C@H](N)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CS)C(N1CCC[C@H]1C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)C(C)C)=O)[C@@H](C)CC)=O)=O)CC(C)C)=O.CC(O)=O |
| Sequence | Thr-Leu-Gly-Ile-Val-Cys-Pro-Ile |
| Sequence Short | TLGIVCPI |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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