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HPV16 E7 (86-93) acetate
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Catalog No. TP1554L
Alias HPV16 E7 (86-93) acetate(160212-93-1 Free base)
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.
HPV16 E7 (86-93) acetate
🥰Excellent
Purity: 96.9100%
Catalog No. TP1554LAlias HPV16 E7 (86-93) acetate(160212-93-1 Free base)
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $54 | In Stock | |
| 5 mg | $111 | In Stock | |
| 10 mg | $158 | In Stock | |
| 25 mg | $266 | In Stock | |
| 50 mg | $371 | In Stock | |
| 100 mg | $517 | In Stock | |
| 200 mg | $697 | In Stock |
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Purity:96.9100%
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Product Introduction
Bioactivity
Chemical Properties
| Description | HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas. |
| In vitro | HPV16 E7 peptide-loaded autologous dendritic cells stimulate a specific cytotoxic CD8+ T-cell response[1]. HPV16 E7 (86-93) acetate specific T cells expand upon in vitro stimulation with cognate peptide-pulsed dendritic cells. HPV16 E7 (86-93) acetate specific T cells are reactive against peptide-pulsed targets. HPV16 E7 (86-93) acetate specific E711-20 T cells are reactive against HPV16 E7 expressing CaSki cell line. Precursor T cells specific for HPV16 E7 (86-93) acetate differentiates into HPV specific effector cells in vitro[2]. |
| In vivo | HPV16 E7 (86-93) acetate in IVS culture has specific T cell expansion without recognizing naturally HPV16 E7 expressing cell line CaSki. HPV16 E7 (86-93) acetate has similar observations in transgenic mice. HPV16 E7 (86-93) acetate induces cytotoxic T lymphocyte responses when loaded on the antigen presenting HLA class I molecules[2]. |
| Synonyms | HPV16 E7 (86-93) acetate(160212-93-1 Free base) |
| Molecular Weight | 875.08 |
| Formula | C39H70N8O12S |
| Smiles | C[C@@H](O)[C@H](N)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CS)C(N1CCC[C@H]1C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)C(C)C)=O)[C@@H](C)CC)=O)=O)CC(C)C)=O.CC(O)=O |
| Sequence | Thr-Leu-Gly-Ile-Val-Cys-Pro-Ile |
| Sequence Short | TLGIVCPI |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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