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Synonyms: type I cytoskeletal 19, KRT19, Keratin-19 (K19), Keratin, type I cytoskeletal 19, Cytokeratin-19 (CK-19)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-KRT19 Antibody (2L986) is a Mouse antibody targeting KRT19. Anti-KRT19 Antibody (2L986) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | type I cytoskeletal 19, KRT19, Keratin-19 (K19), Keratin, type I cytoskeletal 19, Cytokeratin-19 (CK-19) |
| Ig Type | IgG |
| Clone | 2L986 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | ICC/IF=1:100-500; IF=1:100-1500; IHC-Fr=1:100-1500; IHC-P=1:100-1500; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Tissue Specificity | Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagu |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. |
| Immunogen | KLH conjugated synthetic peptide: human Cytokeratin 19 |
| Antigen Species | Human |
| Gene Name | KRT19 |
| Gene ID | |
| Protein Name | Keratin, type I cytoskeletal 19 |
| Uniprot ID | |
| Biology Area | Cytokeratins |
| Function | Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
| Molecular Weight | Theoretical: 44 kDa. Actual: 40 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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