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Anti-CASPR2 Antibody (4V558)
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Catalog No. TMAY-03390
Alias mKIAA0868, contactin associated protein-like 2, Caspr2, 5430425M22Rik
Anti-CASPR2 Antibody (4V558) is a Rabbit antibody targeting CASPR2. Anti-CASPR2 Antibody (4V558) can be used in ELISA.
Anti-CASPR2 Antibody (4V558)
Anti-CASPR2 Antibody (4V558)
😃Good
Catalog No. TMAY-03390Alias mKIAA0868, contactin associated protein-like 2, Caspr2, 5430425M22Rik
Anti-CASPR2 Antibody (4V558) is a Rabbit antibody targeting CASPR2. Anti-CASPR2 Antibody (4V558) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CASPR2 Antibody (4V558) is a Rabbit antibody targeting CASPR2. Anti-CASPR2 Antibody (4V558) can be used in ELISA. |
| Alias | mKIAA0868, contactin associated protein-like 2, Caspr2, 5430425M22Rik |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4V558 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CNTNAP2 / CASPR2 (rM CNTNAP2 / CASPR2; TMPY-01695; NP_001004357.2; Met 1-Ser 1262). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CNTNAP2/CASPR2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. CNTNAP2/CASPR2 is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This protein encoding gene is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation. CNTNAP2/CASPR2 may play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. CNTNAP2/CASPR2 Seems to demarcate the juxtaparanodal region of the axo-glial junction. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse CNTNAP2 / CASPR2 protein (TMPY-01695) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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