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VEGFD Protein, Rat, Recombinant (hFc)

(Synonyms: c-fos induced growth factor (vascular endothelial growth factor D)) Copy Product Info

Synonyms: c-fos induced growth factor (vascular endothelial growth factor D)

Catalog No. TMPY-03200 Copy Product Info
VEGFD Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.6 kDa and the accession number is O35251.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$877-10 days7-10 days
10 µg$1427-10 days7-10 days
20 µg$2337-10 days7-10 days
50 µg$5357-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized recombinant Rat VEGF-Dprotein at 10 µg/mL (100 µl/well) can bind biotinylated mouse VEGFR3-Fc with a linear range of 31.25-2000 ng/mL.
Description
VEGFD Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.6 kDa and the accession number is O35251.
Species
Rat
Expression System
HEK293 Cells
TagN-hFc
Accession NumberO35251
ConstructionA DNA sequence encoding the rat FIGF (NP_113949.1)(Phe94-Arg210) was expressed, fused with the Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu
Protein Purity
> 85 % as determined by SDS-PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonymsc-fos induced growth factor (vascular endothelial growth factor D)
Research Background
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.
Chemical Properties
Molecular Weight41.6 kDa (predicted); 52 kDa (reducing conditions)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: VEGFD Protein, Rat, Recombinant (hFc) chemical structure | VEGFD Protein, Rat, Recombinant (hFc) molecular weight