Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC BTK Degrader-1, a powerful, selective, and orally bioavailable degrader of PROTAC BTK, demonstrates effective reduction in BTK protein levels and tumor suppression. It exhibits IC50 values of 34.51 nM for BTK WT and 64.56 nM for BTK-481S, highlighting its potency and efficacy in targeting and diminishing BTK protein abundance [1].
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Description | PROTAC BTK Degrader-1, a powerful, selective, and orally bioavailable degrader of PROTAC BTK, demonstrates effective reduction in BTK protein levels and tumor suppression. It exhibits IC50 values of 34.51 nM for BTK WT and 64.56 nM for BTK-481S, highlighting its potency and efficacy in targeting and diminishing BTK protein abundance [1]. |
Molecular Weight | 749.86 |
Formula | C43H43N9O4 |
CAS No. | 2801715-13-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PROTAC BTK Degrader-1 2801715-13-7 inhibitor inhibit