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Anti-Phospho-MLKL (S345) Antibody (6R72)
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Catalog No. TMAC-02610
Alias p-MLKL (S345), MLKL (p-S345)
Anti-Phospho-MLKL (S345) Antibody (6R72) is a Rabbit antibody targeting Phospho-MLKL (S345). Anti-Phospho-MLKL (S345) Antibody (6R72) can be used in IHC.
Anti-Phospho-MLKL (S345) Antibody (6R72)
Anti-Phospho-MLKL (S345) Antibody (6R72)
😃Good
Catalog No. TMAC-02610Alias p-MLKL (S345), MLKL (p-S345)
Anti-Phospho-MLKL (S345) Antibody (6R72) is a Rabbit antibody targeting Phospho-MLKL (S345). Anti-Phospho-MLKL (S345) Antibody (6R72) can be used in IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-MLKL (S345) Antibody (6R72) is a Rabbit antibody targeting Phospho-MLKL (S345). Anti-Phospho-MLKL (S345) Antibody (6R72) can be used in IHC. |
| Synonyms | p-MLKL (S345), MLKL (p-S345) |
| Ig Type | IgG |
| Clone | 6R72 |
| Reactivity | Mouse |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-MLKL (phospho S345) antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-MLKL (phospho S345) antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-MLKL (phospho S345) antibody. Counter stained with hematoxylin. |
| Application | |
| Recommended Dose | IHC: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human MLKL around the phosphorylation site of Ser345 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 54 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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