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GPRC5D Protein-VLP, Mouse, Recombinant

(Synonyms: orphan G-protein coupled receptor, MGC129714, MGC129713, GPRC5D) Copy Product Info

Synonyms: orphan G-protein coupled receptor, MGC129714, MGC129713, GPRC5D

Catalog No. TMPK-01193 Copy Product Info
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 39.90 kDa and the accession number is Q9JIL6-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$1967-10 days7-10 days
10 μg$3267-10 days7-10 days
20 μg$5477-10 days7-10 days
50 μg$1,0907-10 days7-10 days
100 μg$1,8507-10 days7-10 days
200 μg$3,3707-10 days7-10 days
500 μg$7,4607-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Mouse GPRC5D VLP (100μl/well) at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.7ng/ml determined by ELISA.
Description
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 39.90 kDa and the accession number is Q9JIL6-1.
Species
Mouse
Expression System
HEK293 Cells
Accession NumberQ9JIL6-1
ConstructionMet1-Leu344
Protein Purity
; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant.
Stability & StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
Synonymsorphan G-protein coupled receptor, MGC129714, MGC129713, GPRC5D
Research Background
Chemical Properties
Molecular Weight39.90 kDa (predicted)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: GPRC5D Protein-VLP, Mouse, Recombinant chemical structure | GPRC5D Protein-VLP, Mouse, Recombinant molecular weight