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TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi)

(Synonyms: VEGI-251, VEGI192A, VEGI, TNFSF15, TL1A, TL1) Copy Product Info

Synonyms: VEGI-251, VEGI192A, VEGI, TNFSF15, TL1A, TL1

Catalog No. TMPK-01011 Copy Product Info
TNFSF15 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 kDa and the accession number is Q5UBV8.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$587-10 days7-10 days
10 µg$927-10 days7-10 days
20 µg$1487-10 days7-10 days
50 µg$2897-10 days7-10 days
100 µg$4877-10 days7-10 days
200 µg$8837-10 days7-10 days
500 µg$1,9507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
1. Immobilized Mouse TNFSF15, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA (QC Test). 2. Mouse DR3, His Tag immobilized on CM5 Chip can bind Mouse TNFSF15, His Tag with an affinity constant of 0.96 nM as determined in SPR assay.
Description
TNFSF15 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 kDa and the accession number is Q5UBV8.
Species
Mouse
Expression System
HEK293 Cells
TagN-His-Avi
Accession NumberQ5UBV8
ConstructionAla61-Leu252
Protein Purity
> 90% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsVEGI-251, VEGI192A, VEGI, TNFSF15, TL1A, TL1
Research Background
TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or colitis and actively participate in the immunological pathways that underlie mucosal homeostasis and intestinal inflammation.Recently, an important role was demonstrated for TL1A/DR3 as potential mediators of intestinal fibrosis that is associated with the presence of gut inflammation.
Chemical Properties
Molecular Weight24.40 kDa (predicted). Due to glycosylation, the protein migrates to 30-38 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi) chemical structure | TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi) molecular weight