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Anti-Alpha-Synuclein Antibody (1O177) is a Mouse antibody targeting Alpha-Synuclein. Anti-Alpha-Synuclein Antibody (1O177) can be used in WB,IP,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $428 | 7-10 days |
Description | Anti-Alpha-Synuclein Antibody (1O177) is a Mouse antibody targeting Alpha-Synuclein. Anti-Alpha-Synuclein Antibody (1O177) can be used in WB,IP,IF. |
Reactivity | Human |
Application | |
Recommended Dose | WB: 1;100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | The synuclein family members, including ?-synuclein (also designated NACP for non-∫-Amyloid component) and ∫-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. ?-synuclein is localized to neuronal cell bodies and synapses. ?-synuclein was first identified as a component of Alzheimer’s disease amyloid plaques. Abnormal platelet function in Alzheimer’s disease has been demonstrated. During megakaryocytic differentiation ?-synuclein has been found to be upregulated, while ∫-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of ?-synuclein has been found in patients with early onset Parkinson’s disease. |
Conjucates | Unconjugated |
Immunogen | Peptide |
Uniprot ID |
Molecular Weight | Theoretical: 19 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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