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Anti-Alpha-Synuclein Antibody (1O177) is a Mouse antibody targeting Alpha-Synuclein. Anti-Alpha-Synuclein Antibody (1O177) can be used in IF,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $428 | 7-10 days | 7-10 days |
| Description | Anti-Alpha-Synuclein Antibody (1O177) is a Mouse antibody targeting Alpha-Synuclein. Anti-Alpha-Synuclein Antibody (1O177) can be used in IF,IP,WB. |
| Synonyms | PD1, PARK4, PARK1, NACP |
| Clone | 1O177 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of α-synuclein expression in non-transfected (A) and human α-synuclein transfected (B)293T whole cell lysates. 2. Western blot analysis of α-synuclein expression in SH-SY5Y whole cell lysate. ![]() ![]() |
| Application | |
| Recommended Dose | WB: 1;100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The synuclein family members, including ?-synuclein (also designated NACP for non-∫-Amyloid component) and ∫-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. ?-synuclein is localized to neuronal cell bodies and synapses. ?-synuclein was first identified as a component of Alzheimer’s disease amyloid plaques. Abnormal platelet function in Alzheimer’s disease has been demonstrated. During megakaryocytic differentiation ?-synuclein has been found to be upregulated, while ∫-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of ?-synuclein has been found in patients with early onset Parkinson’s disease. |
| Conjucates | Unconjugated |
| Immunogen | Peptide |
| Uniprot ID |
| Molecular Weight | Theoretical: 19 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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