Src Protein, Human, Recombinant (His & GST)

Name: Src Protein, Human, Recombinant (His & GST)
Brand: TargetMol
SKU: TMPY-04384
Price: 63 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: SRC1, SRC proto-oncogene, non-receptor tyrosine kinase, p60-Src, c-SRC, ASV) Copy Product Info

Synonyms: SRC1, SRC proto-oncogene, non-receptor tyrosine kinase, p60-Src, c-SRC, ASV

Catalog No. TMPY-04384 Copy Product Info

Purity: 98.5%

Src Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 87.7 kDa and the accession number is P12931-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$63	-	In Stock
10 µg	$100	-	In Stock
20 µg	$163	7-10 days	7-10 days
50 µg	$320	-	In Stock
100 µg	$547	7-10 days	7-10 days
200 µg	$935	7-10 days	7-10 days
500 µg	$1,890	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:98.5%

Appearance:Solution

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	The specific activity was determined to be ＞80 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.
Description	Src Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 87.7 kDa and the accession number is P12931-1.
Species	Human
Expression System	Baculovirus Insect Cells
Tag	His, GST
Accession Number	P12931-1
Construction	A DNA sequence encoding the human SRC (P12931-1) (Met 1-Leu 536) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. Predicted N terminal: Met
Protein Purity	> 90 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 20% gly, 0.3 mM DTT.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	SRC1, SRC proto-oncogene, non-receptor tyrosine kinase, p60-Src, c-SRC, ASV
Research Background	Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity.

Chemical Properties

Molecular Weight

87.7 kDa (predicted); 81 kDa (non-reducing conditions)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.