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PAz-PC

Name: PAz-PC
Brand: TargetMol
SKU: T35956
Rating: 4.5 (1 reviews)

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Catalog No. T35956Cas No. 117746-89-1

Alias PAzePC, Azelaoyl PC, 1-Palmitoyl-2-Azelaoyl PC

PAz-PC (Azelaoyl PC) is a truncated phospholipid oxidation product that enhances endothelial barrier disruption induced by heat-inactivated Staphylococcus aureus (HKSA).

PAz-PC

😃Good

Catalog No. T35956Alias PAzePC, Azelaoyl PC, 1-Palmitoyl-2-Azelaoyl PCCas No. 117746-89-1

PAz-PC (Azelaoyl PC) is a truncated phospholipid oxidation product that enhances endothelial barrier disruption induced by heat-inactivated Staphylococcus aureus (HKSA).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$142	35 days	35 days
5 mg	$663	35 days	35 days
10 mg	$1,130	35 days	35 days
25 mg	$2,530	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	PAz-PC (Azelaoyl PC) is a truncated phospholipid oxidation product that enhances endothelial barrier disruption induced by heat-inactivated Staphylococcus aureus (HKSA).
In vitro	PAz-PC can cause acute lung endothelial cell barrier breakdown. [1] The oxidation of phospholipid PAz-PC can promote the permeability of Bax to mitochondrial membrane. [2]
Synonyms	PAzePC, Azelaoyl PC, 1-Palmitoyl-2-Azelaoyl PC

Chemical Properties

Molecular Weight	665.84
Formula	C₃₃H₆₄NO₁₀P
Cas No.	117746-89-1
Smiles	[C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCCC(O)=O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH 7.2): 1 mg/mL (1.5 mM), Sonication is recommended.

DMF: 1 mg/mL (1.5 mM), Sonication is recommended.

DMSO: 1 mg/mL (1.5 mM), Sonication is recommended.

Ethanol: 8 mg/mL (12.01 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMF/DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	1.5019 mL	7.5093 mL	15.0186 mL	75.0931 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc