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PGPC

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Catalog No. T35959Cas No. 89947-79-5
Alias 1-Palmitoyl-2-glutaryl phosphatidylcholine

PGPC (1-Palmitoyl-2-glutaryl phosphatidylcholine) is an oxidized phospholipid and activates peroxisome proliferator-activated receptor in a concentration-dependent manner.

PGPC

PGPC

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Purity: 99.68%
Catalog No. T35959Alias 1-Palmitoyl-2-glutaryl phosphatidylcholineCas No. 89947-79-5
PGPC (1-Palmitoyl-2-glutaryl phosphatidylcholine) is an oxidized phospholipid and activates peroxisome proliferator-activated receptor in a concentration-dependent manner.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 μg$94-In Stock
1 mg$178-In Stock
5 mg$696-In Stock
10 mg$1,090-In Stock
25 mg$1,650-In Stock
50 mg$2,230-In Stock
100 mg$2,950-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.68%
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Product Introduction

Bioactivity
Description
PGPC (1-Palmitoyl-2-glutaryl phosphatidylcholine) is an oxidized phospholipid and activates peroxisome proliferator-activated receptor in a concentration-dependent manner.
In vitro
PGPC activates peroxisome proliferator-activated receptor in a concentration-dependent manner[3]. PGPC increases VCAM1 and E-selectin expression in human aortic endothelial cells, as well as HAEC binding by monocytes and polymorphonuclear neutrophils, in a concentration-dependent manner[4].
Synonyms1-Palmitoyl-2-glutaryl phosphatidylcholine
Chemical Properties
Molecular Weight609.73
FormulaC29H56NO10P
Cas No.89947-79-5
Smiles[C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCC(O)=O)=O
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: 20 mg/mL (32.8 mM), Sonication is recommended.
DMSO: 1 mg/mL (1.64 mM), Sonication is recommended.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM1.6401 mL8.2004 mL16.4007 mL82.0035 mL
Ethanol
1mg5mg10mg50mg
5 mM0.3280 mL1.6401 mL3.2801 mL16.4007 mL
10 mM0.1640 mL0.8200 mL1.6401 mL8.2004 mL
20 mM0.0820 mL0.4100 mL0.8200 mL4.1002 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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