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LILRA3/CD85e Protein, Human, Recombinant (His)

(Synonyms: LIR-4, LIR4, leukocyte immunoglobulin like receptor A3, ILT-6, ILT6, HM43, HM31, CD85e) Copy Product Info

Synonyms: LIR-4, LIR4, leukocyte immunoglobulin like receptor A3, ILT-6, ILT6, HM43, HM31, CD85e

Catalog No. TMPY-03696 Copy Product Info
Purity: 95.3%
LILRA3/CD85e Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.4 kDa and the accession number is AAH28208.1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$55-In Stock
10 µg$86-In Stock
20 µg$139-In Stock
50 µg$269-In Stock
100 µg$451-In Stock
200 µg$7987-10 days7-10 days
500 µg$1,6907-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:95.3%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
LILRA3/CD85e Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.4 kDa and the accession number is AAH28208.1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberAAH28208.1
ConstructionA DNA sequence encoding the human LILRA3 (AAH28208.1) (Met1-Glu439) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Gly 24
Protein Purity
> 85 % as determined by SDS-PAGE
LILRA3/CD85e Protein, Human, Recombinant (His)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionReconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
SynonymsLIR-4, LIR4, leukocyte immunoglobulin like receptor A3, ILT-6, ILT6, HM43, HM31, CD85e
Research Background
ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
Chemical Properties
Molecular Weight58.4 kDa (predicted); 57-66 kDa (reducing conditions)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: LILRA3/CD85e Protein, Human, Recombinant (His) chemical structure | LILRA3/CD85e Protein, Human, Recombinant (His) molecular weight