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Anti-CD8 beta Antibody (6K410)
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Catalog No. TMAY-01498
Alias CD8b molecule, CD8 β
Anti-CD8 beta Antibody (6K410) is a Rabbit antibody targeting CD8 beta. Anti-CD8 beta Antibody (6K410) can be used in IHC-P.
Anti-CD8 beta Antibody (6K410)
Anti-CD8 beta Antibody (6K410)
😃Good
Catalog No. TMAY-01498Alias CD8b molecule, CD8 β
Anti-CD8 beta Antibody (6K410) is a Rabbit antibody targeting CD8 beta. Anti-CD8 beta Antibody (6K410) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $93 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: IHC-P Reactivity: Human |
| Alias | CD8b molecule, CD8 β |
| Ig Type | Rabbit IgG |
| Clone | 6K410 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human CD8B in human spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CD8B in human lymph node with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD8B / P37 / LEU2 (rh CD8B / P37 / LEU2; TMPY-02925; P10966-1; Met1-Pro170). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD8B (CD8b molecule), also known as P37 and LEU2, contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. P37 gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. CD8 is thought to play a role in the process of T-cell mediated killing. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD8B / P37 / LEU2 Protein (TMPY-02925) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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