IL-18BPd Protein, Mouse, Recombinant (hFc)

Name: IL-18BPd Protein, Mouse, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-00072
Rating: 4.5 (1 reviews)

(Synonyms: Interleukin-18-binding protein, Interleukin 18 Binding Protein Isoform d, Interferon γ-inducing factor-binding protein, Interferon gamma-inducing factor-binding protein, IL-18 BPd, Igifbp) Copy Product Info

Synonyms: Interleukin-18-binding protein, Interleukin 18 Binding Protein Isoform d, Interferon γ-inducing factor-binding protein, Interferon gamma-inducing factor-binding protein, IL-18 BPd, Igifbp

Catalog No. TMPJ-00072 Copy Product Info

Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interaction between IL-18 and IL-18BP has a significant role in the inflammation process. IL-18 BPs have four isoforms, a, b, c and d, which are spliced by different ways. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain which is essential to the binding and neutralizing properties of the binding proteins. The IL-18 BP isoforms b and d lack a complete Ig domain. The expression of IL-18 and the IL-18BP are indentified in immune tissues such as the spleen, but also in nonimmune cells including keratinocytes.

IL-18BPd Protein, Mouse, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
5 μg	$51	7-10 days	7-10 days
10 μg	$79	7-10 days	7-10 days
20 μg	$113	7-10 days	7-10 days
50 μg	$183	7-10 days	7-10 days
100 μg	$335	7-10 days	7-10 days
200 μg	$615	7-10 days	7-10 days
500 μg	$1,390	7-10 days	7-10 days
1 mg	$1,980	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interaction between IL-18 and IL-18BP has a significant role in the inflammation process. IL-18 BPs have four isoforms, a, b, c and d, which are spliced by different ways. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain which is essential to the binding and neutralizing properties of the binding proteins. The IL-18 BP isoforms b and d lack a complete Ig domain. The expression of IL-18 and the IL-18BP are indentified in immune tissues such as the spleen, but also in nonimmune cells including keratinocytes.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q9Z0M9
Amino Acid	Thr29-Ala193
Construction	Thr29-Ala193
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonyms	Interleukin-18-binding protein, Interleukin 18 Binding Protein Isoform d, Interferon γ-inducing factor-binding protein, Interferon gamma-inducing factor-binding protein, IL-18 BPd, Igifbp
Research Background

Chemical Properties

Molecular Weight

60-90 KDa (reducing condition)

Storage & Solubility Information

Storage

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: IL-18BPd Protein, Mouse, Recombinant (hFc) chemical structure | IL-18BPd Protein, Mouse, Recombinant (hFc) molecular weight