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Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. APOE is usually secreted in plasma. Phosphorylation sites are present in the extracellular medium.

| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 5 μg | $80 | In Stock | |
| 10 μg | $129 | In Stock | |
| 20 μg | $232 | In Stock | |
| 50 μg | $513 | In Stock | |
| 100 μg | $693 | 7-10 days | |
| 200 μg | $933 | 7-10 days | |
| 500 μg | $1,390 | 7-10 days | |
| 1 mg | $1,980 | 7-10 days | 
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.  | 
| Description | Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. APOE is usually secreted in plasma. Phosphorylation sites are present in the extracellular medium.  | 
| Species | Mouse  | 
| Expression System | HEK293 Cells  | 
| Tag | C-6xHis | 
| Accession Number | P08226 | 
| Synonyms | Apolipoprotein E,Apo-E,APOE  | 
| Amino Acid | Glu19-Gln311  | 
| Construction | Glu19-Gln311  | 
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) ![]()  | 
| Molecular Weight | 30-40 KDa (reducing condition) | 
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. | 
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. | 
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.  | 
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.  | 
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| Research Background | Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. APOE is usually secreted in plasma. Phosphorylation sites are present in the extracellular medium.  | 

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