CD28H/TMIGD2 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-05440

The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is Q96BF3-1.

CD28H/TMIGD2 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-05440

Pack Size	Price	Availability	Quantity
100 μg	$700	7-10 days
1 mg	$3,910	7-10 days

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Product Information

Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized human HHLA2h at 10 μg/mL (100 μL/well) can bind human TMIGD2-Fc3 , the EC50 of human TMIGD2-Fc3 is 50-200 ng/mL.
Description	The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is Q96BF3-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q96BF3-1
Synonyms	transmembrane and immunoglobulin domain containing 2,TPC1,TMIGD2,IGPR-1,IGPR1
Construction	A DNA sequence encoding the human TMIGD2 ( NP_653216.2) (Met1-Gly150) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Ser 23
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	40.9 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy