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CD28H/TMIGD2 Protein, Human, Recombinant (hFc)

(Synonyms: transmembrane and immunoglobulin domain containing 2, TPC1, TMIGD2, IGPR-1, IGPR1) Copy Product Info

Synonyms: transmembrane and immunoglobulin domain containing 2, TPC1, TMIGD2, IGPR-1, IGPR1

Catalog No. TMPY-05440 Copy Product Info
CD28H/TMIGD2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q96BF3-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$797-10 days7-10 days
10 µg$1297-10 days7-10 days
20 µg$2087-10 days7-10 days
50 µg$4197-10 days7-10 days
100 µg$8127-10 days7-10 days
200 µg$1,1807-10 days7-10 days
500 µg$2,3307-10 days7-10 days
1 mg$4,5307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Human B7-H7, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human CD28H, hFc Tag with the EC50 of 0.89 μg/ml determined by ELISA.
Description
CD28H/TMIGD2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q96BF3-1.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberQ96BF3-1
ConstructionLeu23-Gly150
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonymstransmembrane and immunoglobulin domain containing 2, TPC1, TMIGD2, IGPR-1, IGPR1
Research Background
CD28H is constitutively expressed on all naive T cells. Repetitive antigenic exposure, however, induces a complete loss of CD28H on many T cells, and CD28H negative T cells have a phenotype of terminal differentiation and senescence. After extensive screening in a receptor array, a B7-like molecule, B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H.
Chemical Properties
Molecular Weight40.7 kDa (Predicted); 50-60 kDa (Due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: CD28H/TMIGD2 Protein, Human, Recombinant (hFc) chemical structure | CD28H/TMIGD2 Protein, Human, Recombinant (hFc) molecular weight