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Anti-Meprin alpha/MEP1A Antibody (9X394)

😃Good
Catalog No. TMAY-00320
Alias PPHA, Meprin α/MEP1A, meprin A, α (PABA peptide hydrolase), meprin A, alpha (PABA peptide hydrolase)

Anti-Meprin alpha/MEP1A Antibody (9X394) is a Rabbit antibody targeting Meprin alpha/MEP1A. Anti-Meprin alpha/MEP1A Antibody (9X394) can be used in ELISA.

Anti-Meprin alpha/MEP1A Antibody (9X394)

Anti-Meprin alpha/MEP1A Antibody (9X394)

😃Good
Catalog No. TMAY-00320Alias PPHA, Meprin α/MEP1A, meprin A, α (PABA peptide hydrolase), meprin A, alpha (PABA peptide hydrolase)
Anti-Meprin alpha/MEP1A Antibody (9X394) is a Rabbit antibody targeting Meprin alpha/MEP1A. Anti-Meprin alpha/MEP1A Antibody (9X394) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: ELISA

Reactivity: Human
AliasPPHA, Meprin α/MEP1A, meprin A, α (PABA peptide hydrolase), meprin A, alpha (PABA peptide hydrolase)
Ig Type
Rabbit IgG
Clone
9X394
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human MEP1A (rh MEP1A; TMPY-01737; NP_005579.2; Met1-Gln601).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundMeprin A subunit alpha, also known as MEP1A, and Endopeptidase-2, is a single-pass type I membrane protein that belongs to the peptidase M12A family. MEP1A contains one EGF-like domain, one MAM domain, and one MATH domain. Meprins are unique plasma membrane and secreted metalloproteinases that are highly regulated at the transcriptional and post-translational levels. Meprin alpha and beta subunits are abundantly expressed in kidney and intestinal epithelial cells, are secreted into the urinary tract and intestinal lumen and are found in leukocytes and cancer cells under certain conditions. Meprins are capable of proteolytically degrading extracellular matrix proteins, processing bioactive proteins, and play a role in inflammatory processes. Meprin A and B are highly regulated, secreted and cell-surface homo- and hetero-oligomeric enzymes. Meprins are abundantly expressed in the kidney and intestine. The multidomain alpha and beta subunits have high sequence identity. They have very different substrate specificities, oligomerization potentials, and are differentially regulated. Meprin A appears to be an important therapeutic target and urinary excretion appears to be a potential biomarker of acute kidney injury ( AKI ).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human MEP1A protein (TMPY-01737)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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