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Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
(Synonyms: PFD, FACTOR D, EC 3.4.21.46, EC 3.4.21, DF, Complement factor D, CFD, C3 convertase activator, AMBP-1, ADN, Adipsin) Copy Product InfoSynonyms: PFD, FACTOR D, EC 3.4.21.46, EC 3.4.21, DF, Complement factor D, CFD, C3 convertase activator, AMBP-1, ADN, Adipsin
Catalog No. TMPK-00151 Copy Product Info
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is P03953-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $100 | 7-10 days | 7-10 days | |
| 20 µg | $163 | 7-10 days | 7-10 days | |
| 50 µg | $318 | 7-10 days | 7-10 days | |
| 100 µg | $533 | 7-10 days | 7-10 days | |
| 200 µg | $969 | 7-10 days | 7-10 days | |
| 500 µg | $2,130 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is P03953-1. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | P03953-1 |
| Construction | Ile26-Ser259 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl (pH 7.4). |
| Synonyms | PFD, FACTOR D, EC 3.4.21.46, EC 3.4.21, DF, Complement factor D, CFD, C3 convertase activator, AMBP-1, ADN, Adipsin |
| Research Background | Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. |
| Molecular Weight | 52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| Shipping | Proteins are shipped with blue ice. |
| Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) chemical structure | Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) molecular weight
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