FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 1,050.00 | |
500 μg | 5 days | $ 4,200.00 | |
1 mg | 5 days | $ 6,990.00 |
Description | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
Species | Human |
Expression System | HEK293 |
Tag | N-His-Avi |
Accession Number | Q96RD9-1 |
Synonyms | CD307, FcRL5, FcR-like protein 5, FCRH5MGC119593, DKFZp667F216, BXMAS1, IFGP5, FLJ00397, DKFZp667E2019, CD307e, FcRH5, BXMAS1MGC119592, FLJ00333 |
Construction | Recombinant Biotinylated Human FcRH5/FcRL5 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus. It contains Gln16-Gly851.[Accession |Q96RD9-1] |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | The protein has a predicted MW of 94.19 kDa. Due to glycosylation, the protein migrates to 90-130 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
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Please read the User Guide of Recombinant Proteins for more specific information.
FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated FLJ-00397 CD307 FcRL5 DKFZp667F 216 DKFZp667E 2019 FcR-like protein 5 FLJ 00397 FCRH5MGC119593 DKFZp667F216 BXMAS1 CD-307 BXMAS-1 IFGP 5 FLJ 00333 FCRH5MGC 119593 FLJ-00333 IFGP5 BXMAS1MGC 119592 DKFZp667E-2019 FLJ00397 IFGP-5 FCRH5MGC-119593 DKFZp667E2019 BXMAS 1 CD307e DKFZp667F-216 FcRH5 BXMAS1MGC-119592 BXMAS1MGC119592 FLJ00333 CD 307 recombinant recombinant-proteins proteins protein