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Poricoic acid AM

Name: Poricoic acid AM
Brand: TargetMol
SKU: TN2337
Price: 123 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2337Cas No. 151200-92-9

Poricoic acid AM is a triterpenoid compound derived from Poria cocos, exhibiting anti-tumor activity.

Poricoic acid AM

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Purity: 99.51%

Catalog No. TN2337Cas No. 151200-92-9

Poricoic acid AM is a triterpenoid compound derived from Poria cocos, exhibiting anti-tumor activity.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$123	-	In Stock
5 mg	$297	-	In Stock
10 mg	$496	-	In Stock
25 mg	$793	-	In Stock
50 mg	$1,070	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.51%

Appearance:Solid

Color:White

Resource Download

COA CNMR HNMR HPLC

Product Introduction

Poricoic acid AM AI Summary

Poricoic acid AM demonstrates bioactivity in inhibiting TPA-induced Epstein-Barr virus early antigen activation in Raji cells, with the highest inhibition observed at a 10 mol ratio and a positive effect on cell viability at 70.0%. Additionally, it exhibits cytotoxicity against human HL60 cells and human CRL1579 cells with IC50 values of 15900.0 nM and 88900.0 nM, respectively, as determined by MTT assay after 48 hours..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Poricoic acid AM is a triterpenoid compound derived from Poria cocos, exhibiting anti-tumor activity.

Chemical Properties

Molecular Weight	512.72
Formula	C₃₂H₄₈O₅
Cas No.	151200-92-9
Smiles	[H][C@]1([C@@H](CCC(=C)C(C)C)C(O)=O)[C@H](O)C[C@@]2(C)C3=CC[C@@H](C(C)=C)[C@](C)(CCC(=O)OC)C3=CC[C@]12C
Relative Density.	1.09 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (19.5 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 1 mg/mL (1.95 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9504 mL	9.7519 mL	19.5038 mL	97.5191 mL
5 mM	0.3901 mL	1.9504 mL	3.9008 mL	19.5038 mL
10 mM	0.1950 mL	0.9752 mL	1.9504 mL	9.7519 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc