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LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His)

Catalog No. TMPY-06147
Synonyms: ILT1, LIR7, LIR-7, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2, CD85H

LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.4 kDa and the accession number is Q8N149-1.

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LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 700.00
1 mg 5 days $ 4,570.00
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Biological Description
Technical Params
Product Properties
Description LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.4 kDa and the accession number is Q8N149-1.
Species Human
Expression System HEK293 Cells
Tag C-His
Accession Number Q8N149-1
Synonyms ILT1, LIR7, LIR-7, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2, CD85H
Construction The Human LILRA2 (NP_001124389.2) (Met1-Asn449) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity > 95 % as determined by SDS-PAGE.
Molecular Weight 48.4 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses the innate immune response. It is an activating receptor highly expressed in inflammatory tissues and is involved in granulocyte and macrophage activation. LILRA2 is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophages, neutrophils, basophils, and eosinophils but not on lymphocytes and NK cells. LILRA2 cross-linking on monocytes induces pro-inflammatory cytokines while inhibiting dendritic cell differentiation and antigen presentation. Diseases associated with LILRA2 include Tuberculoid Leprosy and Leprosy 3.

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Keywords

LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His) ILT 1 ILT1 LIR7 LIR 7 ILT-1 LIR-7 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 CD85H recombinant recombinant-proteins proteins protein

 

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